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1

Antiproliferative effect of trichostatin a and hc-toxin in T47D Human breast cancer cells

Ki Eun Joung, Dae-Kee Kim, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

2004

Language:

english

File:

PDF, 831 KB

english, 2004

2

Synthesis and biological evaluation of 1-substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Cheng Hua Jin, Maddeboina Krishnaiah, Domalapally Sreenu, Vura Bala Subrahmanyam, Kota Sudhakar Rao, Annaji Venkata Nagendra Mohan, Chul-Yong Park, Jee-Yeon Son, Yhun Yhong Sheen, Dae-Kee Kim

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 443 KB

english, 2011

3

Comprehensive analysis of differential gene expression profiles on carbon tetrachloride-induced rat liver injury and regeneration

Heekyoung Chung, Doo-Pyo Hong, Ji-Youn Jung, Hyun-Jun Kim, Ki-Seok Jang, Yhun-Yhong Sheen, Joon-Ik Ahn, Yong-Sung Lee, Gu Kong

Journal:

Toxicology and Applied Pharmacology

Year:

2005

Language:

english

File:

PDF, 879 KB

english, 2005

4

Antiestrogen action in breast cancer cells: Modulation of proliferation and protein synthesis, and interaction with estrogen receptors and additional antiestrogen binding sites

Benita S. Katzenellenbogen, Margaret Ann Miller, Alaka Mullick, Yhun Yhong Sheen

Journal:

Breast Cancer Research and Treatment

Year:

1985

Language:

english

File:

PDF, 1.22 MB

english, 1985

5

Estrogen modulation of human breast cancer cell growth

Hyung Ok Lee, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1997

Language:

english

File:

PDF, 491 KB

english, 1997

6

Antiestrogen, trans-tamoxifen modulation of human breast cancer cell growth

Hyung Ok Lee, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1997

Language:

english

File:

PDF, 566 KB

english, 1997

7

Antiestrogen interaction with estrogen receptors and additional antiestrogen binding sites in human breast cancer MCF-7 cells

Mee Ryung Ahn, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1997

Language:

english

File:

PDF, 603 KB

english, 1997

8

Synthesis and biological evaluation of 2-benzylamino-4(5)-(6-methylpyridin-2-yl)-5(4)-([1,2,4]triazolo[1,5-a]-pyridin-6-yl)thiazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Krishnaiah, Maddeboina, Jin, Cheng Hua, Sreenu, Domalapally, Subrahmanyam, Vura Bala, Rao, Kota Sudhakar, Son, Do-Hyun, Park, Hyun-Ju, Kim, Seung Won, Sheen, Yhun Yhong, Kim, Dae-Kee

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 840 KB

english, 2012

9

MMTV/c-Neu transgenic mice as a model to study antitumor activity against breast cancer in vivo

Kyung Nan Min, Yeo Woon Kim, Ki Yoon Kim, Ji Hye Kim, Dae-Kee Kim, Yhun Yhong Sheen

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 82 KB

english, 2006

10

An Evaluation of the Role of Antiestrogen-Binding Sites in Mediating the Growth Modulatory Effects of Antiestrogens: Studies Using t -Butylphenoxyethyl Diethylamine, a Compound Lacking Affinity for the Estrogen Receptor*

SHEEN, YHUN YHONG, SIMPSON, DAVID M., KATZENELLENBOGEN, BENITA S.

Journal:

Year:

1985

Language:

english

File:

PDF, 530 KB

english, 1985

11

Synthesis and biological evaluation of 4(5)-(6-methylpyridin-2-yl)imidazoles and -pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Dae-Kee Kim, Yeon-Im Lee, Yeon Woo Lee, Purushottam M. Dewang, Yhun Yhong Sheen, Yeo Woon Kim, Hyun-Ju Park, Jakyung Yoo, Ho Soon Lee, Yong-Kook Kim

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 1.16 MB

english, 2010

12

Effects of hydroxylated flavonoids on the ethoxyresorufin O-deethylase and benzo(α)pyrene hydroxylase

Sun Ho Han, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1996

Language:

english

File:

PDF, 889 KB

english, 1996

13

Identification of EBP50 as a specific biomarker for carcinogens via the analysis of mouse lymphoma cellular proteome

Yoen Jung Lee, In-Kwon Choi, Yhun Yhong Sheen, Sue Nie Park, Ho Jeong Kwon

Journal:

Molecules and Cells

Year:

2012

Language:

english

File:

PDF, 620 KB

english, 2012

14

Discovery of N -((4-([1,2,4]Triazolo[1,5- a ]pyridin-6-yl)-5-(6-methylpyridin-2-yl)-1 H -imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A Highly Potent, Selective, and Orally Bioavailable Inhibitor of TGF-β Type I Receptor Kinase as Cancer Immunotherapeutic/Antifibrotic Agent

Jin, Cheng Hua, Krishnaiah, Maddeboina, Sreenu, Domalapally, Subrahmanyam, Vura B., Rao, Kota S., Lee, Hwa Jeong, Park, So-Jung, Park, Hyun-Ju, Lee, Kiho, Sheen, Yhun Yhong, Kim, Dae-Kee

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.81 MB

english, 2014

15

TGF-� Type I Receptor Kinase Inhibitor EW-7197 Suppresses Cholestatic Liver Fibrosis by Inhibiting HIF1a-Induced Epithelial Mesenchymal Transition

Kim, Min-Jin, Park, Sang-A, Kim, Chun Hwa, Park, So-Yeon, Kim, Jung-Shin, Kim, Dae-Kee, Nam, Jeong-Seok, Sheen, Yhun Yhong

Journal:

Cellular Physiology and Biochemistry

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

16

TIMP-1 mediates TGF-β-dependent crosstalk between hepatic stellate and cancer cells via FAK signaling

Park, Sang-A, Kim, Min-Jin, Park, So-Yeon, Kim, Jung-Shin, Lim, Woosung, Nam, Jeong-Seok, Yhong Sheen, Yhun

Journal:

Scientific Reports

Year:

2015

Language:

english

File:

PDF, 2.35 MB

english, 2015

17

Assessment of the estrogenicity of isoflavonoids, using MCF-7-ERE-Luc cells

Ki Eun Joung, Yeo Woon Kim, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

2003

Language:

english

File:

PDF, 678 KB

english, 2003

18

Characterization of acetylcholinesterase from Korean electric ray and comparison withTorpedo californica

So Young Ahn, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1995

Language:

english

File:

PDF, 728 KB

english, 1995

19

Synthesis and biological evaluation of 5-(fluoro-substituted-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)imidazoles as inhibitors of transforming growth factor-β type I receptor kinase

Krishnaiah, Maddeboina, Jin, Cheng Hua, Sheen, Yhun Yhong, Kim, Dae-Kee

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 599 KB

english, 2015

20

EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells

Chul-Yong Park, Dae-Kee Kim, Yhun Yhong Sheen

Journal:

Year:

2011

Language:

english

File:

PDF, 739 KB

english, 2011

21

Trout P450IA1: cDNA and Deduced Protein Sequence, Expression in Liver, and Evolutionary Significance

HEILMANN, LARRY J., SHEEN, YHUN-YHONG, BIGELOW, SANFORD W., NEBERT, DANIEL W.

Journal:

Year:

1988

Language:

english

File:

PDF, 2.22 MB

english, 1988

22

How Does “Regulatory Practice” Create Discrepancies in Drug Label Information Between Asian and Western Countries? Different Label Information for Direct Oral Anticoagulants Approved in the United States, Europe, Korea, and Japan

Cho, Il Young, Choi, Ki Hwan, Sheen, Yhun Yhong

Journal:

Therapeutic Innovation & Regulatory Science

Year:

2018

Language:

english

File:

PDF, 231 KB

english, 2018

23

Quantitative assessment of estrogenic activity in the water environment of Korea by the E-SCREEN assay

Seung-Min Oh, Se-Young Choung, Yhun-Yhong Sheen, Kyu-Hyuck Chung

Journal:

Science of The Total Environment

Year:

2000

Language:

english

File:

PDF, 220 KB

english, 2000

24

Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinolin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Cheng Hua Jin, Maddeboina Krishnaiah, Domalapally Sreenu, Kota Sudhakar Rao, Vura Bala Subrahmanyam, Chul-Yong Park, Jee-Yeon Son, Yhun Yhong Sheen, Dae-Kee Kim

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 607 KB

english, 2011

25

Stimulation of troutCYP1Agene expression in mouse HEPA-1 cells by 3-methylcholanthrene

Soo Young Lee, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1997

Language:

english

File:

PDF, 790 KB

english, 1997

26

ChemInform Abstract: Synthesis and Biological Evaluation of 1-Substituted-3-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo [1,5-a]pyridin-6-yl)pyrazoles as Transforming Growth Factor-β Type 1 Receptor Kinase Inhibitors.

Cheng Hua Jin, Maddeboina Krishnaiah, Domalapally Sreenu, Vura Bala Subrahmanyam, Kota Sudhakar Rao, Annaji Venkata Nagendra Mohan, Chul-Yong Park, Jee-Yeon Son, Yhun Yhong Sheen, Dae-Kee Kim

Journal:

Year:

2012

Language:

english

File:

PDF, 36 KB

english, 2012

27

Moesin is a biomarker for the assessment of genotoxic carcinogens in mouse lymphoma

Yoen Jung Lee, In-Kwon Choi, Yhun Yhong Sheen, Sue Nie Park, Ho Jeong Kwon

Journal:

Molecules and Cells

Year:

2012

Language:

english

File:

PDF, 805 KB

english, 2012

28

EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung

Chul-Yong Park, Jee-Yeon Son, Cheng Hua Jin, Jeong-Suk Nam, Dae-Kee Kim, Yhun Yhong Sheen

Journal:

European Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.85 MB

english, 2011

29

Estrogen receptor enhances the antiproliferative effects of trichostatin A and HC-toxin in human breast cancer cells

Kyung Nan Min, Min Jung Cho, Dae-Kee Kim, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

2004

Language:

english

File:

PDF, 1.11 MB

english, 2004

30

Isolation of 5′-untranslational region of troutCYP1A1gene

Yong Nam Roh, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1996

Language:

english

File:

PDF, 1.18 MB

english, 1996

31

Histone deacetylase inhibitor stimulateCYP3A4proximal promoter activity in hepg2 cells

Ja Young Kim, Mee Ryung Ahn, Dae-Kee Kim, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

2004

Language:

english

File:

PDF, 1.08 MB

english, 2004

32

4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type I receptor kinase

Jin, Cheng Hua, Krishnaiah, Maddeboina, Sreenu, Domalapally, Subrahmanyam, Vura Bala, Park, Hyun-Ju, Park, So-Jung, Sheen, Yhun Yhong, Kim, Dae-Kee

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 990 KB

english, 2014

33

Trichostatin a, a histone deacetylase inhibitor stimulateCYP3A4proximal promoter activity in hepa-I cells

Mee Ryung Ahn, Dae-Kee Kim, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

2004

Language:

english

File:

PDF, 993 KB

english, 2004

34

An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial–mesenchymal transition

Park, Chul-Yong, Min, Kyung Nan, Son, Jee-Yeon, Park, So-Yeon, Nam, Jeong-Seok, Kim, Dae-Kee, Sheen, Yhun Yhong

Journal:

Year:

2014

Language:

english

File:

PDF, 2.61 MB

english, 2014

35

EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling

Park, Sang-A, Kim, Min-Jin, Park, So-Yeon, Kim, Jung-Shin, Lee, Seon-Joo, Woo, Hyun Ae, Kim, Dae-Kee, Nam, Jeong-Seok, Sheen, Yhun Yhong

Journal:

Cellular and Molecular Life Sciences

Year:

2015

Language:

english

File:

PDF, 11.84 MB

english, 2015

36

Comparison of glucuronidating activity of two human cDNAs, UDPGTh1 and UDPGTh2

Soon Sun Kim, Ida S. Owens, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1997

Language:

english

File:

PDF, 561 KB

english, 1997

37

The impact of size on tissue distribution and elimination by single intravenous injection of silica nanoparticles

Minjung Cho, Wan-Seob Cho, Mina Choi, Sueng Jun Kim, Beom Seok Han, Sheen Hee Kim, Hyoung Ook Kim, Yhun Yhong Sheen, Jayoung Jeong

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 6.86 MB

english, 2009

38

Cloning and expression of human liver UDP-glucuronosyltransferase cDNA, UDPGTh2

Misook Dong, Ida S. Owens, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1997

Language:

english

File:

PDF, 708 KB

english, 1997

39

Synthesis and biological evaluation of 1-substituted-3(5)-(6-methylpyridin-2-yl)-4-(quinoxalin-6-yl)pyrazoles as transforming growth factor-β type 1 receptor kinase inhibitors

Cheng Hua Jin, Domalapally Sreenu, Maddeboina Krishnaiah, Vura Bala Subrahmanyam, Kota Sudhakar Rao, Annaji Venkata Nagendra Mohan, Chul-Yong Park, Jee-Yeon Son, Do-Hyun Son, Hyun-Ju Park, Yhun Yhong

Journal:

European Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 731 KB

english, 2011

40

Expression of human liver 3, 4-catechol estrogens UDP-Glucuronosyltransferase cDNA in COS 1 cells

Mee Ryung Ahn, Ida S. Owens, Yhun Yhong Sheen

Journal:

Archives of Pharmacal Research

Year:

1997

Language:

english

File:

PDF, 612 KB

english, 1997

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